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Bupropion acts as an norepinephrine-dopamine reuptake inhibitor (NDRI).
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It is an atypical antidepressant, different from most commonly prescribed antidepressants such as selective serotonin reuptake inhibitors (SSRIs).
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Bupropion was first made by Nariman Mehta and patented by Burroughs Wellcome in 1969, which later became part of what is now Glaxo Smith Kline.
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